Drug Study: Cefipime

DRUG	CLASSIFICATION	DOSE	ACTION	CONTRAINDICATIONS	SIDE EFFECTS	NURSING RESPONSIBILITIES
Generic Name: Cefipime Brand Name: Orazinc	Classification: Cephalosporin Indication: Cefepime is usually reserved to treat moderate-severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment   of febrile neutropenia.[3] Cefepime has good activity against important pathogens including Pseudomonas aeruginosa, Staphylococcus aureus, and multiple drug resistant Streptococcus pneumoniae.	Dose: 5mL Route: PO Frequency: OD	The combination of the syn-configuration of the methoxyimino moiety and the aminothiazolyl moiety confers extra stability to β-lactamase enzymes produced by many bacteria. The N-methylpyrrolidine moiety increases penetration into Gram-negative bacteria. These factors increases the activity of cefepime against otherwise resistant organisms including Pseudomonas aeruginosa andStaphylococcus aureus.	· Pregnancy and breast-feeding · Hypersensitivity	confusion, hallucinations, or convulsiones o se desmaya. seizure (black-out or convulsions); diarrhea that is watery or bloody; skin rash, bruising, severe tingling, numbness, pain, muscle weakness; fever, chills, body aches, flu symptoms; easy bruising or bleeding, unusual weakness; or sore throat and headache with a severe blistering, peeling, and red skin rash.	·         Do not use cefepime if ever had an allergic reaction to another cephalosporin or to a penicillin without first talking to the ordering physician ·         Ask for hypersensitivity to drugs ·         Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If with   diarrhea that is watery or has blood in it, call inform the physician